
Heart failure with preserved ejection fraction in patients with type 2 diabetes mellitus: pathophysiology and treatment options
Author(s) -
А. А. Борисов,
Anna Gvozdeva,
Ф Т Агеев
Publication year - 2021
Publication title -
medicinskij vestnik ûga rossii
Language(s) - English
Resource type - Journals
eISSN - 2618-7876
pISSN - 2219-8075
DOI - 10.21886/2219-8075-2021-12-2-6-15
Subject(s) - ejection fraction , heart failure , medicine , diabetes mellitus , cardiology , type 2 diabetes mellitus , heart failure with preserved ejection fraction , pathophysiology , intensive care medicine , endocrinology
Type 2 diabetes mellitus is known to increase the risk of the development of heart failure with preserved ejection fraction and worsen its symptoms. To date, no specific treatment has been shown to reduce morbidity and mortality in patients with heart failure with preserved ejection fraction. In this review, the authors summarized the existing evidence on how diabetes mellitus can promote the development and progression of heart failure with preserved ejection fraction. The authors also addressed medications including experimental ones that can potentially be beneficial in patients of this group.