Open AccessAutoimmune polyglandular syndrome type 3
Author(s) -
Г. Р. Газизова,
М. Р. Шайдуллина,
Ф. В. Валеева,
А. И. Галиева
Publication year - 2020
Publication title -
medicinskij vestnik ûga rossii
Language(s) - English
Resource type - Journals
eISSN - 2618-7876
pISSN - 2219-8075
DOI - 10.21886/2219-8075-2020-11-4-78-83
Subject(s) - vitiligo , medicine , pernicious anemia , endocrine system , thyroiditis , type 1 diabetes , autoimmune disease , thyroid , disease , endocrine disease , dermatology , autoimmune thyroiditis , immunology , diabetes mellitus , endocrinology , anemia , hormone
Autoimmune polyglandular syndrome type 3 (APS type 3) is a combination of autoimmune thyroid damage in combination with one or more autoimmune endocrine or non-endocrine diseases. It is represented by three subtypes: APS 3A (graves ‘ Disease, or Hashimoto’s thyroiditis and type 1 diabetes mellitus), APS 3B (autoimmune thyroid disease and pernicious anemia), APS 3C (autoimmune thyroid disease and vitiligo, alopecia, and/or other organ-specific autoimmune diseases). Clinical observations of patients with type 3 APS are presented: characteristic clinical syndromes and clinical and laboratory characteristics of patients. These clinical examples demonstrate the importance of thorough examination, alertness and knowledge of endocrinologists about the possibility of developing polyglandular lesions of the endocrine system, the importance of timely prescribed treatment and interdisciplinary interaction of doctors.