Open AccessФотоокисление тетрагидробиоптерина как основа фототерапии витилиго
Author(s) -
Т.А. Телегина,
Ю.Л. Вечтомова,
М.С. Крицкий,
А.С. Низамутдинов,
Э.И. Мадиров,
Д.А. Макарова,
А.А. Буглак
Publication year - 2022
Publication title -
optika i spektroskopiâ
Language(s) - English
Resource type - Journals
eISSN - 2782-6694
pISSN - 0030-4034
DOI - 10.21883/os.2022.05.52432.14-22
Subject(s) - tetrahydrobiopterin , photochemistry , chemistry , xenon , kinetics , physics , organic chemistry , nitric oxide , nitric oxide synthase , quantum mechanics
The kinetics of photooxidation of tetrahydrobiopterin was investigated, the quantum yields of the formation of dihydropterin dimers were calculated when using a xenon lamp, a tunable UV laser and a UV LED as UV radiation sources. A comparative analysis of the effectiveness of these sources for the photooxidation process of tetrahydrobiopterin allowed us to conclude that the most effective for the purposes of vitiligo phototherapy are, apparently, UV LED sources with emission maxima in the region of 325 nm.