Open AccessКомплексное изучение особенностей поглощения сыворотки крови крыс с экспериментальным раком печени-=SUP=-*-=/SUP=-
Author(s) -
М.М. Назаров,
О. П. Черкасова,
Ekateri. Lazareva,
А. Б. Бучарская,
Н.А. Наволокин,
В. В. Тучин,
Alexander P. Shkurinov
Publication year - 2019
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/os.2019.06.47775.53-19
Subject(s) - refractometer , terahertz radiation , refractive index , chemistry , materials science , analytical chemistry (journal) , optics , optoelectronics , physics , chromatography
The THz-TDS in the frequency range of 0.05–1.0 THz has been used to study the blood serum of rats in dynamics of experimental liver cancer. THz transmission spectra of samples from healthy rats and for 14 and 28 days after implantation of tumor cells have a similar shape, but differ in amplitude. The protein content decreases for the case of 28th day of the implantation, as it have been measured by biochemical analysis. The observed changes in the THz response are explained by a decrease in the number of protein molecules and water bounded with it. Those results correlate with decrease in the refractive index in the visible and near IR range from 480 to 1550 nm, measured with a multiwave refractometer.