Open AccessЭлектростимуляция дермальных фибробластов человека на электропроводящей матрице
Author(s) -
K. A. Kolbe,
M. A. Shishov,
И.Ю. Сапурина,
Н. В. Смирнова,
V. V. Kodolova-Chukhontseva,
Е.Н. Дресвянина,
Almaz Kamalov,
В.Е. Юдин
Publication year - 2021
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/jtf.2021.12.51772.160-21
Subject(s) - chitosan , biocompatible material , carbon nanotube , materials science , stimulation , composite number , matrix (chemical analysis) , ionic bonding , biomedical engineering , scaffold , biophysics , nanotechnology , composite material , chemistry , ion , medicine , neuroscience , biology , biochemistry , organic chemistry
Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials (±100 mV) were studied; the scaffold demonstrated high stability in the course of prolonged electric cycling. It was shown that preliminary electrical stimulation facilitated proliferative activity of human dermal fibroblasts in comparison to that of intact cells.