Open AccessКонтроль структуры имплантов и систем доставки лекарственных соединений при помощи метода сканирующей электронной микроскопии с энергодисперсионным анализом
Author(s) -
Н.Н. Сударева,
Н.Н Сапрыкина,
А.Л. Буянов,
К.А. Колбе,
C.А. Божкова
Publication year - 2020
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/jtf.2020.09.49690.410-19
Subject(s) - polyelectrolyte , materials science , self healing hydrogels , chemical engineering , coating , cellulose , scanning electron microscope , bacterial cellulose , osseointegration , porosity , polymer , nanotechnology , implant , composite material , polymer chemistry , medicine , surgery , engineering
Scanning electron microscopy (SEM) in combination with energy-dispersive spectrometric (EDS) analysis was used for the first time in the studies of composition of several materials being developed for medical uses. Cartilage implants were obtained on the basis of poly(acrylamide) hydrogels, bacterial and plant cellulose samples; dynamics of changes in implant composition and composition of near-boundary zones was demonstrated. This dynamics is indicative of dependence of osteointegration process on the nature of cellulose sample. The systems intended for protein delivery and based on porous vaterites (СаСО3) were studied; these delivery systems include the composite products in which the matrices (СаСО3 cores) are coated with several pairs of polyelectrolyte layers. It was demonstrated that structures of polyelectrolyte coatings can be determined depending on the coating methods; localization of encapsulated protein in СаСО3 cores was established.