Open AccessТерагерцевый отклик от биоткани как основа диагностики и лечения в персонифицированной медицине
Author(s) -
Н.Т. Баграев,
Л.Е. Клячкин,
А.М. Маляренко,
К.Б. Таранец
Publication year - 2020
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/jtf.2020.09.49682.18-20
Subject(s) - terahertz radiation , oligonucleotide , optoelectronics , silicon , spectrometer , materials science , common emitter , biological tissue , computer science , biological system , dna , chemistry , optics , physics , biology , biochemistry
A spectrometer based on silicon nanosandwiches (SNS) is proposed for solving problems of personalized medicine. Silicon nanosandwich (SNS) structures combine the properties of a terahertz (THz) emitter and a recorder of THz response from biological tissue. It has been demonstrated that recording the current-voltage characteristics (CVC) of the SNS structure allows us to analyze the spectral composition of the THz response from biological tissue and thus determine the relative contribution of various proteins and amino acids that make up the DNA oligonucleotides and their compounds. At the same time, the obvious advantages of the proposed technique are visible, since the THz response can be detected directly from living biological tissue, which can form the basis for the rapid analysis of DNA oligonucleotides. Further study of the behavior of the spectral peaks of the SNS C – V characteristics is of great interest for methods of personalized diagnosis and treatment, as demonstrated by the example of testing various control groups of subjects.