Open AccessОптимизация параметров импульсных РЧ-последовательностей для МРТ-исследований в присутствии магнитных наночастиц
Author(s) -
Ю.В. Богачев,
А.В. Никитина,
В.В. Фролов,
Я.Ю. Марченко,
Б.П. Николаев
Publication year - 2020
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/jtf.2020.09.49678.419-19
Subject(s) - magnetic resonance imaging , contrast (vision) , nuclear magnetic resonance , gadolinium , radio frequency , materials science , computer science , physics , radiology , medicine , artificial intelligence , telecommunications , metallurgy
The influence of parameters of various pulsed radio frequency (RF) sequences on the contrast of magnetic resonance (MR) images is investigated. A program for modeling of magnetic resonance imaging (MRI) tomograms and determining the optimal values of pulse RF sequences parameters to achieve the best contrast of MR images has been developed. This program has been tested for MRI studies using negative contrast agents based on magnetic iron oxide nanoparticles and positive contrast agents based on gadolinium. Their influence on MR signal intensity depending on concentration is analyzed. Recommendations on the choice of optimal values of RF sequences parameters for MRI diagnostics using contrasting agents are developed.