Open AccessРазработка ЯМР-релаксометра для определения динамики намагниченности протонов воды живых тканей и его использование для оценки возрастных изменений
Author(s) -
Ю.И. Неронов,
Д.Д. Косенков
Publication year - 2019
Publication title -
žurnal tehničeskoj fiziki
Language(s) - English
Resource type - Journals
eISSN - 1726-748X
pISSN - 0044-4642
DOI - 10.21883/jtf.2019.07.47810.424-18
Subject(s) - relaxation (psychology) , paramagnetism , connective tissue , magnetization , nuclear magnetic resonance , sarcopenia , spin (aerodynamics) , materials science , chemistry , condensed matter physics , physics , magnetic field , medicine , thermodynamics , anatomy , quantum mechanics , pathology
A desktop NMR relaxometer was created, which allows determining spin–spin relaxation times of water protons in living tissues. Spin relaxation times of protons of water reflect changes in the mean number of paramagnetic centers, since the presence of these centers increases the magnetization recovery rate of water protons in living tissues tens of times. In particular, this method allowed observing age-related changes (sarcopenia) related to substitution of connective tissue for muscle fibers. Relaxometers of this type are comfortable to use and are promising devices for analysis and diagnostics of changes and disorders of metabolic processes.