Open AccessCardiovascular disorders in patients with Zika Virus: integrative review
Author(s) -
Lucas Dalvi Armond Rezende,
Paula de Souza Silva Freitas,
Davi de Souza Catabriga,
Helaine Jacinta Salvador Mocelin,
Ana Lúcia da Silva,
Lavinya Moreira Silva,
Bruno Henrique Fiorin
Publication year - 2022
Publication title -
revista ciências em saúde
Language(s) - English
Resource type - Journals
ISSN - 2236-3785
DOI - 10.21876/rcshci.v12i1.1210
Subject(s) - medicine , atrial fibrillation , zika virus , pathophysiology , intensive care medicine , cardiology , virus , virology
Objective: To describe the primary cardiovascular disorders manifested in patients infected with the zika virus and understand the pathophysiological process. Methods: This integrative literature review occurred in January 2021 through the PICO strategy, which answered the guiding question: “What are the main cardiovascular disorders manifested in patients infected with zika virus?” For this, a time interval of 5 years was defined, using the descriptors “Zika Virus”,“Heart” and “Cardiovascular Diseases” in English, Portuguese and Spanish. The contemplated databases were MEDLINE, LILACS, and BDENF. Results: There were a total of 77,872 articles, of which, after the exclusion and inclusion processes, it was summarized in eight articles included in this review. The main cardiovascular findings present were apical muscular ventricular septal defect and ostium secundum, in addition to atrial fibrillation and heart failure with reduced ejection fraction. Conclusions: Further studies with more robustness that clearly establish the mechanism of cellular tropism for cardiac muscle cells and involve the pathophysiological process of cardiac alterations more clearly and reliably are needed.