Open AccessMethylation of Tumor Suppressive miRNAs in Plasma from Patients With Pancreaticobiliary Diseases
Author(s) -
Koushiro Ohtsubo,
Kunio Miyake,
Sachiko Arai,
Koji Fukuda,
Chiaki Suzuki,
HIROSHI KOTANI,
Azusa Tanimoto,
AKIHIRO NISHIYAMA,
SHIGEKI NANJO,
Kaname Yamashita,
SHINJI TAKEUCHI,
SEIJI YANO
Publication year - 2022
Publication title -
cancer diagnosis and prognosis
Language(s) - English
Resource type - Journals
ISSN - 2732-7787
DOI - 10.21873/cdp.10120
Subject(s) - microrna , methylation , pancreatic cancer , cancer research , cancer , medicine , dna methylation , biliary tract cancer , biology , gastroenterology , oncology , gene , genetics , gene expression , gemcitabine
We previously reported the usefulness of aberrant methylation of tumor suppressive miRNAs in bile to discriminate pancreaticobiliary cancers (PBCs) from benign pancreaticobiliary diseases (BD). Here we performed a methylation analysis of plasma miRNAs to identify miRNAs specific for PBCs.