Open AccessIntra-tumoral FGFR2 Expression Predicts Prognosis and Chemotherapy Response in Advanced HER2-positive Gastric Cancer Patients
Author(s) -
Naohiko Nakamura,
Daisuke Kaida,
Yasuto Tomita,
Takashi Miyata,
Tomoharu Miyashita,
Hideto Fujita,
Shinichi Kinami,
Nobuhiko Ueda,
Hiroyuki Takamura
Publication year - 2022
Publication title -
cancer diagnosis and prognosis
Language(s) - English
Resource type - Journals
ISSN - 2732-7787
DOI - 10.21873/cdp.10107
Subject(s) - trastuzumab , medicine , chemotherapy , immunohistochemistry , univariate analysis , gastrectomy , cancer , oncology , fibroblast growth factor receptor 2 , gastroenterology , multivariate analysis , fibroblast growth factor , receptor , breast cancer
This study aimed to evaluate the relationship between clinical outcomes and intra-tumoral fibroblast growth factor receptor 2 (FGFR2) expression in human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) patients who had undergone HER2-targeted chemotherapy.