Open AccessA Brief Overview of Oncogenes and Signal Transduction Pathways in Gynecological Cancer
Author(s) -
Emmanuel N Kontomanolis,
Antonios Koutras,
Zacharias Fasoulakis,
Athanasios Syllaios,
Michail Diakosavvas,
Kyveli Angelou,
PANAGIOTIS SYMEONIDIS,
Athina Samara,
Vasilios Pergialiotis,
Nikolaos Garmpis,
Dimitrios Schizas,
Athanasios Pagkalos,
Athanasios Chionis,
Georgios Daskalakis,
Thomas Ntounis
Publication year - 2022
Publication title -
cancer diagnosis and prognosis
Language(s) - English
Resource type - Journals
ISSN - 2732-7787
DOI - 10.21873/cdp.10087
Subject(s) - cervical cancer , carcinogenesis , ovarian cancer , uterine cancer , signal transduction , cancer , female reproductive system , vulvar cancer , cancer research , reproductive system , biology , medicine , oncology , genetics
Gynecological cancer is the cancer that originates in the female reproductive system. According to the anatomical location of the cancer, it is distinguished into cervical, uterine, vaginal, ovarian, and vulvar cancer. Oncogenes and tumor catalytic genes play a key role in the genesis and development of gynecological cancer. This article presents the signaling pathways and expression of oncogenes that take place in the carcinogenesis of the female reproductive system.