Hyaluronic Acid May Be a Predictive Biomarker for Thrombocytopenia and Liver Dysfunction After Oxaliplatin-based Chemotherapy | Zendy

Takashi Miyata | Zendy; Yasuto Tomita | Zendy; Yuta Sannomiya | Zendy; Taigo Nagayama | Zendy; Ryosuke Kin | Zendy; Hisashi Nishiki | Zendy; Akifumi Hashimoto | Zendy; Yoritaka Fujii | Zendy; Seiko Miura | Zendy; Daisuke Kaida | Zendy; Naohiko Nakamura | Zendy; Tomoharu Miyashita | Zendy; Hideto Fujita | Zendy; Nobuhiko Ueda | Zendy; Hiroyuki Takamura | Zendy

Open Access

Hyaluronic Acid May Be a Predictive Biomarker for Thrombocytopenia and Liver Dysfunction After Oxaliplatin-based Chemotherapy

Author(s) -

Takashi Miyata,

Yasuto Tomita,

Yuta Sannomiya,

Taigo Nagayama,

Ryosuke Kin,

Hisashi Nishiki,

Akifumi Hashimoto,

Yoritaka Fujii,

Seiko Miura,

Daisuke Kaida,

Naohiko Nakamura,

Tomoharu Miyashita,

Hideto Fujita,

Nobuhiko Ueda,

Hiroyuki Takamura

Publication year - 2022

Publication title -

cancer diagnosis and prognosis

Language(s) - English

Resource type - Journals

ISSN - 2732-7787

DOI - 10.21873/cdp.10071

Subject(s) - oxaliplatin , medicine , capecitabine , colorectal cancer , chemotherapy , hyaluronic acid , gastroenterology , pathological , oncology , cancer , anatomy

Following oxaliplatin-based chemotherapy, approximately half of all colorectal cancer patients develop sinusoidal obstruction syndrome (SOS). SOS can be monitored by measuring splenic volume; however, obtaining this measurement is not a simple process. In this study, we evaluated changes in hyaluronic acid (HA) concentrations as a simpler marker of SOS.

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