High Expression of PEA15 Is Associated With Patient Survival in Malignant Pleural Mesothelioma | Zendy

Shajedul Islam | Zendy; Takao Kitagawa | Zendy; Yasuhiro Kuramitsu | Zendy

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High Expression of PEA15 Is Associated With Patient Survival in Malignant Pleural Mesothelioma

Author(s) -

Shajedul Islam,

Takao Kitagawa,

Yasuhiro Kuramitsu

Publication year - 2021

Publication title -

cancer diagnosis and prognosis

Language(s) - English

Resource type - Journals

ISSN - 2732-7787

DOI - 10.21873/cdp.10049

Subject(s) - medicine , mesothelioma , biomarker , immunohistochemistry , oncology , mesothelium , overall survival , cancer , cancer research , pathology , mesothelial cell , biology , biochemistry

Malignant pleural mesothelioma (MPM) is a rare but very aggressive tumor that is primarily pleural in origin. The 5-year overall survival rate of patients with MPM has not improved despite therapeutic advances. Therefore, biomarker discovery to identify premalignant or early malignant tumors of the mesothelium are crucial. PEA15 is a cytoplasmic protein that is involved in various human malignancies, including MPM. However, the clinicopathological involvement of PEA15 in MPM has not yet been documented.

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