STUDY OF THE INFLUENCE OF 6-(40 -IODOPHENYL)-2,3-DIHYDRO [2,1-B] THIAZOLE AT THYROID FUNCTION MALE WHITE RATS WITH EXPERIMENTAL AUTOIMMUNE THYROIDITIS | Zendy

Н. Г. Малова | Zendy; L. A. Sirotenko | Zendy; И. В. Комарова | Zendy; E. S. Anikeeva | Zendy; A. V. Spiridonov | Zendy; A. N. Sova | Zendy; Vladimir Vakula | Zendy; F. G. Yaremenko | Zendy

Open Access

STUDY OF THE INFLUENCE OF 6-(40 -IODOPHENYL)-2,3-DIHYDRO [2,1-B] THIAZOLE AT THYROID FUNCTION MALE WHITE RATS WITH EXPERIMENTAL AUTOIMMUNE THYROIDITIS

Author(s) -

Н. Г. Малова,

L. A. Sirotenko,

И. В. Комарова,

E. S. Anikeeva,

A. V. Spiridonov,

A. N. Sova,

Vladimir Vakula,

F. G. Yaremenko

Publication year - 2016

Publication title -

problems of endocrine pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.141

H-Index - 2

eISSN - 2518-1432

pISSN - 2227-4782

DOI - 10.21856/j-pep.2016.3.05

Subject(s) - autoimmune thyroiditis , thyroglobulin , thyroid , medicine , thyroiditis , thyroid function , endocrinology , immunology

The study of new biologically active compound PL-308 with immunomodulating properties on the thyroid function in rats with experimental autoimmune thyroiditis. It was determined that the introduction of PL-308 reduces autoimmune aggression by lowering the level of antibodies to thyroglobulin, increases the number of all subpopulations of T-lymphocytes, in particular Tsuppressors. It was observed normalization of the functional state of the thyroid gland.

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