Open AccessFEATURES OF IMMUNOINFLAMMATORY ACTIVATION AND ENDOTHELIAL FUNCTION IN PATIENTS WITH CORONARY HEART DISEASE ASSOCIATED WITH HYPOTHYROIDISM
Author(s) -
N. S. Mykhailovska,
T. V. Oleynik
Publication year - 2015
Publication title -
problemi endokrinnoï patologìï
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.141
H-Index - 2
eISSN - 2518-1432
pISSN - 2227-4782
DOI - 10.21856/j-pep.2015.4.05
Subject(s) - medicine , euthyroid , concomitant , cardiology , coronary artery disease , thyroid function , hormone , thyroid disease , heart disease , endothelial dysfunction , thyroid , endocrinology
he presence of hypothyroidism in patients with coronary heart disease contributes to its progression. It was found that in patients with coronary heart disease associated with hypothyroidism, there is an increase markers of immunoinflammatory activation and endothelial dysfunction compared both to coronary heart disease patients without concomitant thyroid disease and patients with coronary artery disease with the structural changes of the thyroid gland in euthyroid state. Established the presence of correlations of neopterin levels, plasminogen activator inhibitor-1, endothelin-1 with hormones of the pituitary-thyroid level in patients with coronary heart disease with concomitant hypothyroidism.