PANCREATIC AND EXTRA PANCREATIC EFFECTS OF GLYMEPIRIDE | Zendy

Н. А. Кравчун | Zendy

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PANCREATIC AND EXTRA PANCREATIC EFFECTS OF GLYMEPIRIDE

Author(s) -

Н. А. Кравчун

Publication year - 2021

Publication title -

problems of endocrine pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.141

H-Index - 2

eISSN - 2518-1432

pISSN - 2227-4782

DOI - 10.21856/j-pep.2015.3.16

Subject(s) - lipotoxicity , hyperinsulinemia , insulin resistance , diabetes mellitus , medicine , pancreas , type 2 diabetes , insulin , endocrinology

Insulin resistance (IR) and hyperinsulinemia (GI) play a leading role in the development of macrovascular complications in type 2 diabetes mellitus (DM), which are the main cause of mortality in these patients. Taking into account the decisive importance of gluco- and lipotoxicity in the development of microangiopathies, the main goal of antidiabetic pharmacological correction is to influence IR and dysfunction of β-cells of the pancreas

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