Open AccessPECULARITIES OF CARBOHYDRARE METABOLISM IN PATIENTS WITH PROLACTINOMAS DURING SUPRESSIVE AGONIST DOPAMINE’S THERAPY
Author(s) -
О. O. Khyzhnyak,
Teona Gogitidze
Publication year - 2021
Publication title -
problemi endokrinnoï patologìï
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.141
H-Index - 2
eISSN - 2518-1432
pISSN - 2227-4782
DOI - 10.21856/j-pep.2015.3.09
Subject(s) - cabergoline , endocrinology , bromocriptine , medicine , prolactin , dopamine agonist , prolactinoma , agonist , carbohydrate metabolism , dopamine , hyperinsulinemia , insulin , hormone , insulin resistance , receptor , dopaminergic
The article presents data of carbohydrate metabolism at the stages of long-term (12months) suppressive therapy dopamine agonist cabergoline in 61 patients with prolactinomas. It was proved that the normalization of prolactin levels during therapy reduces fasting glucose, HbA1c of patients, independently of gender. Insulin levels become normal in men with prior hyperinsulinemia and overweight. Pharmacology-induced hypoprolaktinemya not lead to disorders of carbohydrate metabolism.