Open AccessSERUM LEVEL OF VCAM-1, ICAM-1, E-SELECTIN IN TYPE 2 DIABETES AND OBESETY
Author(s) -
L. A. Mogylnytska
Publication year - 2021
Publication title -
problemi endokrinnoï patologìï
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.141
H-Index - 2
eISSN - 2518-1432
pISSN - 2227-4782
DOI - 10.21856/j-pep.2015.3.06
Subject(s) - medicine , dyslipidemia , diabetes mellitus , type 2 diabetes , endocrinology , body mass index , insulin resistance , obesity , vcam 1 , icam 1 , immunology , cell adhesion molecule
The study revealed an elevation of serum levels of VCAM-1, ICAM-1, E-selectin in obese and nonobese type 2 diabetes patients and obese subjects without diabetes. An elevation of serum levels of VCAM-1, ICAM-1, E-selectin is associated with hyperglycemia and dyslipidemia in non-obese type 2 diabetes patients. An increase of VCAM-1, ICAM-1, E-selectin is associated with body mass index, an markers of insulin resistance and lipid metabolism in obese type 2 diabetes patients and obese subjects without diabetes. Detect changes point to the development of endothelial dysfunction in patients with type 2 diabetes with different body weight and obese subjects without diabetes.