Open AccessFEATURES OF CHANGES IN CIRCADIAN RHYTHM OF CIRCULATING LEVELS OF INSULIN AND GLUCOSE IN THE METABOLIC SYNDROME INDUCED EXPERIMENTAL HYPOPINEALISM
Author(s) -
T. V. Mishchenko,
A. I. Gladkih,
В. В. Полторак
Publication year - 2021
Publication title -
problemi endokrinnoï patologìï
Language(s) - English
Resource type - Journals
eISSN - 2518-1432
pISSN - 2227-4782
DOI - 10.21856/j-pep.2015.1.10
Subject(s) - circadian rhythm , hyperinsulinemia , medicine , endocrinology , insulin , rhythm , metabolic syndrome , biology , carbohydrate metabolism , bacterial circadian rhythms , insulin resistance , diabetes mellitus , circadian clock
In the experimental study on young adult male rabbits it was found leveling of circadian rhythm in insulin concentration and violation of circadian pattern of glucose (inversion, which is replaced by leveling) in the dynamics of the formation of metabolic syndrome, which develops in the hypopinealism induced by long-term exposure to low-light in the dark. Change in the circadian rhythm of secretion of insulin, glucose, and hyperinsulinemia that result of chronic disturbance of natural light/dark cycle, are the basis of the manifestation of the metabolic syndrome in hypopinealism.