Open AccessOsseointegration of Titanium and Steel Additive Manufactured Implant in Rabbit Tibia under External Fixation: Comparative Study
Author(s) -
А. А. Еманов,
В. П. Кузнецов,
Е. Н. Горбач,
М. В. Стогов,
Е. А. Киреева,
Е. Н. Овчинников
Publication year - 2020
Publication title -
travmatologiâ i ortopediâ rossii
Language(s) - English
Resource type - Journals
eISSN - 2542-0933
pISSN - 2311-2905
DOI - 10.21823/2311-2905-2020-26-2-98-108
Subject(s) - osseointegration , implant , dentistry , tibia , titanium , bone tissue , fixation (population genetics) , biomaterial , medicine , materials science , surgery , biomedical engineering , metallurgy , population , environmental health
Relevance . The main goals of successful prosthesis remain ensuring the osseointegration and infectious safety of implants. The purpose of the study — the comparative analysis of osseointegration of titanium and steel additive manufactured implants in the rabbit tibia under additional fixation by Ilizarov apparatus. Materials and Methods . The study was performed on 20 chinchilla male rabbits. The animals of the first group (n = 8 ) were implanted a stainless steel product EOS PH1 (EOS, Germany), the animals of the second group (n = 12) — a titanium alloy Ti6Al4V product. The implant was additionally fixed by Ilizarov apparatus. The implants were processed with additive technology by selective laser fusion at the EOSINT M 280 installation (EOS, Germany). The survival and safety of the implants were assessed using clinical, histological, laboratory and statistical methods. Results . The implant fall due to chronic inflammation was found in 2 animals of group 1 and none in group 2. The formation of weakly mineralized bone tissue on the surface of the implant was noted in 3 weeks in all cases. The bone became more mineralized by the 12 th week of the experiment. However, in group 2, the calcium content and Ca / P ratio of the newly formed bone tissue at the 3 rd and 12 th week after implantation were significantly higher than in the animals of group 1. This indicated the greater maturity of the bone tissue in animals of group 2 at all stages of the experiment. In group 1, the compact plate osteoporosis and calcium-phosphorus balance disturbance were greater. Conclusion . The results of the study indicate that the survival rate (osseointegration) and safety of the product made of the titanium alloy were higher compared with the stainless steel product.