Open AccessTHE PROPHYLAXIS OF VERTEBRAL COMPRESSION REFRACTURES USING ZOLEDRONIC ACID
Author(s) -
Александр Юрьевич Кочиш,
S Ivanov,
Владислав Николаевич Хрулёв
Publication year - 2010
Publication title -
travmatologiâ i ortopediâ rossii
Language(s) - English
Resource type - Journals
eISSN - 2542-0933
pISSN - 2311-2905
DOI - 10.21823/2311-2905-2010-0-2-113-115
Subject(s) - zoledronic acid , medicine , osteoporosis , compression (physics) , vertebral compression fracture , femoral neck , surgery , lumbar , dual energy , urology , bone mineral , materials science , composite material
29 women with postmenopausal osteoporosis, complicated by compression vertebral fractures were treated by infusion of zoledronic acid, 5 mg. The results were assessed using dual-energy X-ray absorptiometry. By 12 months BMD increased both in lumbar spine (mean 5,2% (σ=0,17) and in femoral neck (mean 3,9% (σ=0,20)); by 24 month the mean increase were 6,3% и 4,0% (σ=0,33) respectively. No new compression vertebral fractures were found.