Open AccessDeath due to Acute Massive Pulmonary Thromboembolism Associated with Risperidone
Author(s) -
Filiz Eren,
T. Inanir Nursel,
Bülent Eren,
Eser Bayraktar,
Okan Yıldız,
N. Gundogmus Umit,
Tomáš Vojtíšek
Publication year - 2019
Publication title -
galician medical journal
Language(s) - English
Resource type - Journals
ISSN - 2414-1518
DOI - 10.21802/gmj.2019.2.12
Subject(s) - medicine , autopsy , pulmonary embolism , risperidone , atropine , quetiapine , cause of death , antipsychotic , atypical antipsychotic , thrombosis , anesthesia , surgery , schizophrenia (object oriented programming) , psychiatry , disease
The antipsychotic drug risperidone, which is extensively used, has also many side effects, as increased risk of stroke, thrombosis, and pulmonary embolism have been reported. We present a case of a 38 year-old-woman with psychiatric disorder who got worse in her home and died in the hospital. Throughout autopsy, during the internal examination, multiple thrombi in the pulmonary artery branches were observed; however, there were no pathology findings in the lower extremity veins. Blood chemistry test revealed 4 ng/ml of risperidone, 37 ng/ml of quetiapine and atropine; chemical examination of urine detected atropine, quetiapine, risperidone. Death occurred due to acute massive pulmonary thromboembolism. We aimed to discuss this case with autopsy and histopathologic findings, laboratory results in medico-legal literature.