Evaluation of learning memory activity of Unmad Gaja Kesari Rasa II in Animal Models

In recent era there is competition in each and every field, so there is lot of mental stress or mentaldisorder seen. In modern medicine there are various drugs such as antipsychotic, antiepileptic, moodstabilizer etc. which have certain adverse effect such as drowsiness, dizziness, memory loss etc. ButAyurveda certainly has an answer, there are total 112 formulations mentioned in classical text forphysco neurological disorder i.e., Unmad and Apasmar, out of these there are total 25 herbo-mineralformulations and Unmad Gaja Kesari Rasa II (UGK II) is one of them. Present study was done toevaluate Learning memory effect of Unmad Gaja Kesari Rasa II a herbo-mineral compound. Cook’s andwidely model was used to evaluate learning memory activity. Total 30 wistar rats were classified into5 groups each containing 6 rats. Human dose was extrapolated with extrapolating factor 0.018 anddrug dose was given to control I and II, standard, test x and 2x group, after that learning andRelearning trails were given and avoidance, escape and no response was observed. It has beenestablished that UGK II (Rasa Kamdhenu i.e.; R.K Unmad Chikitsa/9-12) has effective role in learningand memory activity.