Premium
CCl 4 ‐Enhanced Ultrasonic Irradiation for Ciprofloxacin Degradation and Antibiotic Activity
Author(s) -
Wei Hong,
Shi Jingzhuan,
Yang Xiaoyu,
Wang Jiawei,
Li Kebin,
He Qiang
Publication year - 2018
Publication title -
water environment research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.356
H-Index - 73
eISSN - 1554-7531
pISSN - 1061-4303
DOI - 10.2175/106143017x15131012153077
Subject(s) - ciprofloxacin , chemistry , degradation (telecommunications) , wastewater , aqueous solution , antibacterial activity , chromatography , nuclear chemistry , antibiotics , radical , biodegradation , microbiology and biotechnology , bacteria , organic chemistry , biochemistry , waste management , telecommunications , biology , computer science , engineering , genetics
In this study, an ultrasound/CCl 4 system was used to degrade the fluoroquinolone antibiotic, ciprofloxacin, in aqueous solution. The effect of CCl 4 concentration and initial solution pH on ciprofloxacin degradation were investigated. The results showed that ciprofloxacin degraded effectively under an ultrasound/CCl 4 system, with degradation efficiency increasing from 0.51% to 50.92%, when the CCl 4 concentration ranged from 0.0 to 41.4 mmol/L in 40 min. Radical scavenging experiments certified that both •OH and chlorine‐containing radicals contributed to ciprofloxacin degradation. Eight intermediates were detected using ultra high‐performance liquid chromatography‐mass spectrometry (UHPLC‐MS) method, including three chloro‐intermediates. Based on these results, the possible degradation pathways of ciprofloxacin are proposed. Agar diffusion tests with E. coli and S. aureus showed that ciprofloxacin's antibacterial activity was completely removed in 40 min. This study indicates that an ultrasound/CCl 4 system can degrade ciprofloxacin and remove its antibacterial activity, and thus is a promising process for treating fluoroquinolone antibiotics in wastewater.