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Cytokine Responses in Gills of Capoeta umbla as Biomarkers of Environmental Pollution
Author(s) -
Danabas Durali,
Yildirim Nuran Cikcikoglu,
Yildirim Numan,
Onal Ayten Oztufekci,
Uslu Gulsad,
Unlu Erhan,
Danabas Seval,
Ergin Cemil,
Tayhan Nilgun
Publication year - 2016
Publication title -
water environment research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.356
H-Index - 73
eISSN - 1554-7531
pISSN - 1061-4303
DOI - 10.2175/106143016x14504669767616
Subject(s) - gill , pollution , environmental pollution , tumor necrosis factor alpha , environmental chemistry , fish <actinopterygii> , biology , environmental science , veterinary medicine , fishery , ecology , immunology , environmental protection , chemistry , medicine
Immunological biomarkers reflect the effects of exposure to environmental contaminants. In this study, the suitability and sensitivity of cytokine responses, interleukin1β (IL‐1β), interleukin‐6 (IL‐6), tumor necrosis factor‐alpha (TNF‐α) in gill tissues of Capoeta umbla (Heckel, 1843), collected from different regions, as early warning indices of environmental pollution and ecosystem health was evaluated. Fish and water samples were taken from ten stations in March and September 2011 and 2012. Tumor necrosis factor‐α, IL‐1β and IL‐6 levels were determined in samples of the gill tissues by using an ELISA kit. Significant variations of TNF‐α, IL‐1β and IL‐6 levels observed between stations and seasons. The results of this study show that seasonal variations of cytokine responses in gills of Capoeta umbla are sensitive to the contaminants present in Uzuncayir Dam Lake (Tunceli, Turkey) water and are valuable biomarkers for environmental pollution and ecosystem health.