Premium
Degradation and Metabolite Production of Tylosin in Anaerobic and Aerobic Swine‐Manure Lagoons
Author(s) -
Kolz A. C.,
Moorman T. B.,
Ong S. K.,
Scoggin K. D.,
Douglass E. A.
Publication year - 2005
Publication title -
water environment research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.356
H-Index - 73
eISSN - 1554-7531
pISSN - 1061-4303
DOI - 10.2175/106143005x41618
Subject(s) - tylosin , manure , anaerobic exercise , metabolite , degradation (telecommunications) , biodegradation , environmental science , environmental chemistry , pulp and paper industry , environmental engineering , chemistry , waste management , biology , microbiology and biotechnology , agronomy , antibiotics , engineering , biochemistry , organic chemistry , physiology , telecommunications
Watershed contamination from antibiotics is becoming a critical issue because of increased numbers of confined animal‐feeding operations and the use of antibiotics in animal production. To understand the fate of tylosin in manure before it is land‐applied, degradation in manure lagoon slurries at 22°C was studied. Tylosin disappearance followed a biphasic pattern, where rapid initial loss was followed by a slow removal phase. The 90% disappearance times for tylosin, relomycin (tylosin D), and desmycosin (tylosin B) in anaerobically incubated slurries were 30 to 130 hours. Aerating the slurries reduced the 90% disappearance times to between 12 and 26 hours. Biodegradation and abiotic degradation occur, but strong sorption to slurry solids was probably the primary mechanism of tylosin disappearance. Dihydrodesmycosin and an unknown degradate with molecular mass of m/z 934.5 were detected. Residual tylosin remained in slurry after eight months of incubation, indicating that degradation in lagoons is incomplete and that residues will enter agricultural fields.