Open Accesseffectiveness testing of l-carnitine on the quality of spermatozoa and testosterone hormone in white rats (Rattus norvegicus) feeding with high fat
Author(s) -
Ni Wayan Sukma Antari,
Ida Ayu Manik Damayanti,
Nadya Treesna Wulansari
Publication year - 2021
Publication title -
international journal of health and medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2632-9433
DOI - 10.21744/ijhms.v4n1.1525
Subject(s) - testosterone (patch) , carnitine , hormone , analysis of variance , medicine , motility , biology , endocrinology , andrology , genetics
This study aims to determine the increase in the quality of spermatozoa and testosterone after giving L-carnitine to white rats (Rattus norvegicus). This study was conducted by giving L-carnitine as a treatment for 42 days in white rats with a dose variation of 100 mg/kg bw, 150 mg/kg bw, and 200 mg/kg bw and user controls as a comparison. The variables observed in this study were the quality of spermatozoa, namely: morphology, motility, viability, membrane integrity, and seeing the levels of the hormone testosterone. The research data were processed using a computer statistical program (SPSS 22.0 for Windows) using the One Way Anova test. The results showed that giving high doses of L-carnitine supplements for a long time could cause decreased spermatozoa quality, namely: morphology, motility, viability, membrane integrity and decreased levels of the hormone testosterone.