Open AccessThe Comprehensive Appraisal of COVID-19: Its’ Clinical Panorama from Virology till Management and Beyond
Author(s) -
H. Iftikhar,
Nayema Zehra Rizvi Saiyeda
Publication year - 2020
Publication title -
coronaviruses
Language(s) - English
Resource type - Journals
eISSN - 2666-7975
pISSN - 2666-7967
DOI - 10.2174/2666796701999200701132336
Subject(s) - pandemic , public health , covid-19 , medicine , middle east respiratory syndrome , china , global health , disease , intensive care medicine , virology , political science , infectious disease (medical specialty) , pathology , law
Severe acute respiratory syndrome, caused by SARS-CoV-2 disease (COVID-19), was firstreported in China, and has laid the entire globe at a standstill, with an uncertain future, and a possibleeconomic disaster. The World Health Organization (WHO), on March 11th 2020, avowed COVID-19 apandemic considering its global pervasiveness. The multi-dimensional challenges include the combatwith present available treatment options while simultaneously hastening scientific research for the developmentof definitive therapeutics and vaccine for this pandemic. The research advancement related toearlier epidemics of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome(MERS) by the same coronavirus family provides the understanding of basic and clinical virology,pathogenesis and therapeutics of SARS-CoV-2. The dearth of definitive therapeutics and vaccine rendersCOVID-19 pandemic a public health challenge globally. This comprehensive review of virology,pathogenesis, and management will abet quarters of public health authorities and medical fraternity tobetter understand COVID-19.