Open AccessUrinary Biomarkers of Oxidative Stress in Atrial Fibrillation
Author(s) -
Lei Meng,
Ricko Wong,
Man Yin Tsui,
Gary Tse,
Guangping Li,
Tong Liu,
Gregory Y.H. Lip
Publication year - 2018
Publication title -
the open biomarkers journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.184
H-Index - 5
ISSN - 1875-3183
DOI - 10.2174/1875318301808010024
Subject(s) - oxidative stress , atrial fibrillation , inflammation , oxidative phosphorylation , oxidative damage , medicine , urine , cardiology , chemistry , biochemistry
There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.