Open AccessMethicillin Resistant Staphylococcus aureus and Extended Spectrum Beta-lactamase Producing Enterobacteriaceae: A Therapeutic Challenge in the 21st Century
Author(s) -
Eric S. Donkor,
Francis S. Codjoe
Publication year - 2019
Publication title -
the open microbiology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.502
H-Index - 27
ISSN - 1874-2858
DOI - 10.2174/1874285801913010094
Subject(s) - staphylococcus aureus , antimicrobial stewardship , enterobacteriaceae , antibiotic resistance , antibiotics , multiple drug resistance , microbiology and biotechnology , infection control , public health , methicillin resistant staphylococcus aureus , medicine , biology , intensive care medicine , bacteria , escherichia coli , biochemistry , genetics , nursing , gene
Antimicrobial resistance is one of the greatest global threats to human health in recent times and it limits the achievement of several of the Sustainable Development Goals. Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-Lactamase (ESBL) producing Enterobacteriaceae are among the most important multidrug resistant bacterial pathogens. MRSA and ESBL-producing Enterobacteriaceae have evolved significantly over the last few decades with important clinical and epidemiological implications. Given the slow progress of development of new antibiotics in recent times, it is likely that these multidrug resistant pathogens will have a greater impact on public health in the 21 st Century, unless other effective control measures are instituted. Effective infection control strategies coupled with antibiotic stewardship programs are required to limit the spread and burden of MRSA and ESBL-producing Enterobacteriacae .