Open AccessInvolvement of the Nervous System in Systemic Sclerosis
Author(s) -
Elīna Polunosika,
Daina Pastare,
Līga Jaunozoliņa,
Guntis Karelis
Publication year - 2022
Publication title -
the open neurology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 16
ISSN - 1874-205X
DOI - 10.2174/1874205x-v16-e2112241
Subject(s) - medicine , scleroderma (fungus) , disease , central nervous system , systemic scleroderma , medical history , systemic disease , presentation (obstetrics) , physical examination , multisystem disease , pathology , localized scleroderma , dermatology , nervous system , connective tissue disease , autoimmune disease , surgery , fibrosis , psychiatry , inoculation
Scleroderma is a rare heterogeneous multisystem autoimmune disease. The disease is characterized by structural abnormalities of the small blood vessels. Scleroderma affects all organs of the body. Skin manifestations are commonly reported, but peripheral nervous system (PNS) and central nervous system (CNS) involvement has been less frequently reported. Neurological manifestations are broad, and it is challenging for clinicians to confirm a diagnosis of scleroderma. Case Presentation: In our case, a 53-year-old white woman had extensive clinical presentations: skin rashes and symptoms from internal organs, CNS, and PNS during the previous 11 years. She had not undergone any specific treatment because diagnosis has not been made in the early stages. Conclusion: It is important to make the diagnosis as early as possible and start treatment with immunomodulatory and immunosuppressant medication, as it affects the patient's disease progression, quality of life, and mortality. A detailed medical history, physical examination, and laboratory and radiology findings help us to identify and diagnose scleroderma. But unfortunately, it was late, and the patient died. This case guides us to be more careful and make the diagnosis of scleroderma earlier in the future.