Cytotoxic, DNA Cleavage and Pharmacokinetic Parameter Study of Substituted Novel Furan C-2 Quinoline Coupled 1, 2, 4-Triazole and Its Analogs | Zendy

R. Anantacharya | Zendy; Nayak Devappa Satyanarayan | Zendy; Bhuvanesh Sukhlal Kalal | Zendy; Vinitha Ramanath Pai | Zendy

Open Access

Cytotoxic, DNA Cleavage and Pharmacokinetic Parameter Study of Substituted Novel Furan C-2 Quinoline Coupled 1, 2, 4-Triazole and Its Analogs

Author(s) -

R. Anantacharya,

Nayak Devappa Satyanarayan,

Bhuvanesh Sukhlal Kalal,

Vinitha Ramanath Pai

Publication year - 2018

Publication title -

the open medicinal chemistry journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.294

H-Index - 18

ISSN - 1874-1045

DOI - 10.2174/1874104501812010060

Subject(s) - quinoline , chemistry , cytotoxic t cell , dna , furan , mtt assay , cleavage (geology) , stereochemistry , biochemistry , biology , cell growth , organic chemistry , in vitro , paleontology , fracture (geology)

Furan, quinoline and triazoles are known for their wide spectrum biologically active molecules. A series of novel furan C-2 quinoline and 1, 2, 4-triazole (FQT) coupled hybrids were designed and synthesized to evaluate for their DNA cleavage and cytotoxic studies.

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