Open AccessInsulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway
Author(s) -
Shuang Yao,
Jun Zhang,
Yuxia Zhan,
Yan Shi,
Yan Yu,
Lu Zheng,
Ning Xu,
Guanghua Luo
Publication year - 2020
Publication title -
endocrine, metabolic and immune disorders. drug targets
Language(s) - English
Resource type - Journals
eISSN - 2212-3873
pISSN - 1871-5303
DOI - 10.2174/1871530319666191023125820
Subject(s) - medicine , endocrinology , insulin resistance , protein kinase b , glucose homeostasis , biology , insulin receptor , carbohydrate metabolism , insulin , lipid metabolism , apolipoprotein b , phosphorylation , biochemistry , cholesterol
Previous clinical studies have suggested that apolipoprotein M (apoM) is involved in glucose metabolism and plays a causative role in insulin sensitivity.