Open AccessMonosubstituted Coumarins Inhibit Epinephrine-induced Platelet Aggregation
Author(s) -
Fausto Alejandro Jiménez-Orozco,
Sergio Galicia-Zapatero,
Edgar López-López,
José L. Medina-Franco,
Fernando León Cedeño,
Mirthala Flores-García,
Ana Marı́a Mejı́a-Domı́nguez,
Aurora de la Peña-Dı́az
Publication year - 2022
Publication title -
cardiovascular and hematological agents in medicinal chemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 39
eISSN - 1875-6182
pISSN - 1871-5257
DOI - 10.2174/1871525719666210427132808
Subject(s) - epinephrine , coumarin , chemistry , platelet , pharmacology , platelet aggregation inhibitor , agonist , in vitro , platelet aggregation , in silico , platelet activation , biochemistry , biophysics , receptor , medicine , aspirin , organic chemistry , biology , gene
The aim of this study was to evaluate the in vitro effect of coumarin and 15 monosubstituted derivatives on the inhibition of human platelet aggregation induced by various proaggregatory agonists, particularly by epinephrine.