Open AccessEvaluation of the Anti-Inflammatory Activities of Diclofenac Sodium, Prednisolone and Atorvastatin in Combination with Ascorbic Acid
Author(s) -
Tanvir Ahmed,
Sabrina Rahman Archie,
Asef Faruk,
Fabliha Ahmed Chowdhury,
Abdullah Al Shoyaib,
Chowdhury Rafiqul Ahsan
Publication year - 2020
Publication title -
anti-inflammatory and anti-allergy agents in medicinal chemistry
Language(s) - English
Resource type - Journals
eISSN - 1875-614X
pISSN - 1871-5230
DOI - 10.2174/1871523018666190514112048
Subject(s) - ascorbic acid , diclofenac sodium , diclofenac , pharmacology , atorvastatin , prednisolone , carrageenan , inflammation , drug , medicine , edema , anti inflammatory , chemistry , food science
Inflammation is our body's normal defense mechanism, but in some cases, it may be responsible for causing different kinds of disorders. Several antiinflammatory drugs are present for the treatment of these disorders; however, the conventional anti-inflammatory drugs cause side effects when used in the long term and therefore, it is better to use them in a low dose for a shorter duration of time. This study was designed to find out whether there is an augmentation of the therapeutic effectiveness of the antiinflammatory drugs like diclofenac sodium (NSAID), prednisolone (steroid) and atorvastatin (statin) when used in combination with ascorbic acid (antioxidant).