Open AccessAn Algorithm to Improve the Speed of Semi and Non-specific Enzyme Searches in Proteomics
Author(s) -
Zach Rolfs,
Robert J. Millikin,
Lloyd M. Smith
Publication year - 2020
Publication title -
current bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 29
eISSN - 2212-392X
pISSN - 1574-8936
DOI - 10.2174/1574893615999200429123334
Subject(s) - redundancy (engineering) , computer science , search algorithm , database search engine , fragment (logic) , identification (biology) , algorithm , search engine , tandem mass spectrometry , computational biology , chemistry , mass spectrometry , information retrieval , biology , chromatography , botany , operating system
The identification of non-specifically cleaved peptides in proteomics and peptidomics poses a significant computational challenge. Current strategies for the identification of such peptides are typically time consuming and hinder routine data analysis.