
Severe Group A and Group B Streptococcus Diseases at a Pediatric ICU: Are they Still Sensitive to the Penicillins?
Author(s) -
Kam Lun Hon,
Theodore Chow,
Tsun S Cheung,
Wai Pang Lam,
Lok T Hung,
K. W. So,
I P Margaret,
Suyun Qian
Publication year - 2020
Publication title -
current clinical pharmacology
Language(s) - English
Resource type - Journals
eISSN - 2212-3938
pISSN - 1574-8847
DOI - 10.2174/1574884714666190926124714
Subject(s) - medicine , clindamycin , streptococcus , group b , pediatric intensive care unit , erythromycin , mechanical ventilation , sepsis , penicillin , group a , intensive care unit , mortality rate , pediatrics , antibiotics , microbiology and biotechnology , biology , genetics , bacteria
Group A β-hemolytic Streptococcus (GAS) and Group B streptococcus (GBS) are two common pathogens that are associated with many diseases in children. Severe infections as a result of these two streptococci are albeit uncommon but associated with high mortality and morbidity, and often necessitate intensive care support. This paper aims to review the mortality and morbidity of severe infection associated with GAS and GBS isolations at a Pediatric Intensive Care Unit (PICU).