Open AccessInvestigation of the Roles of New Antiepileptic Drugs and Serum BDNF Levels in Efficacy and Safety Monitoring and Quality of Life: A Clinical Research
Author(s) -
Meral Oran Demir,
Emel Oğuz Akarsu,
Hava Özlem Dede,
Nerses Bebek,
Sevda Yıldız,
Betül Baykan,
Ahmet Gökhan Akkan
Publication year - 2020
Publication title -
current clinical pharmacology
Language(s) - English
Resource type - Journals
eISSN - 2212-3938
pISSN - 1574-8847
DOI - 10.2174/1574884714666190312145409
Subject(s) - oxcarbazepine , medicine , lamotrigine , epilepsy , quality of life (healthcare) , worry , zonisamide , neuropsychology , antiepileptic drug , adverse effect , topiramate , pharmacology , anesthesia , cognition , gastroenterology , psychiatry , carbamazepine , anxiety , nursing
We aimed to determine the therapeutic drug monitoring (TDM) features and the relation to Brain-Derived Neurotrophic Factor (BDNF) of frequently used new antiepileptic drugs (NADs) including lamotrigine (LTG), oxcarbazepine (OXC), zonisamide (ZNS) and lacosamide (LCM). Moreover, we investigated their effect on the quality of life (QoL).