Open AccessAssociation between Omentin-1 and Coronary Artery Disease: Pathogenesis and Clinical Research
Author(s) -
Lütfü Aşkın,
Hakan Duman,
Ali Gökhan Özyıldız,
Okan Tanrıverdi,
Serdar Türkmen
Publication year - 2020
Publication title -
current cardiology reviews
Language(s) - English
Resource type - Journals
eISSN - 1875-6557
pISSN - 1573-403X
DOI - 10.2174/1573403x16666200511085304
Subject(s) - medicine , adipokine , dyslipidemia , coronary artery disease , pathogenesis , disease , adipose tissue , cardiology , waist , metabolic syndrome , blood pressure , apelin , obesity , insulin resistance , receptor
Like other adipokines, omentin-1 is secreted from visceral adipose tissue and plays a vital role in the development of chronic inflammatory diseases, including cardiovascular events. Recent studies have shown that circulating omentin-1 levels are associated with various metabolic risk factors, such as high blood pressure, increased waist circumference, dyslipidemia, and glucose intolerance. The decrease in serum omentin level is an independent predictor of Coronary Artery Disease (CAD) and is associated with the severity of this disease. Since there is no relevant review in the literature, we aimed to summarize the studies on the relationship between omentin-1 and CAD.