Open AccessPharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
Author(s) -
Reyisha Taximaimaiti,
Xingguang Luο,
Xiaoping Wang
Publication year - 2021
Publication title -
current neuropharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.955
H-Index - 73
eISSN - 1875-6190
pISSN - 1570-159X
DOI - 10.2174/1570159x19666210517115706
Subject(s) - medicine , restless legs syndrome , sleep hygiene , insomnia , sleep (system call) , excessive daytime sleepiness , deep brain stimulation , disease , movement disorders , parkinson's disease , psychological intervention , sleep disorder , physical medicine and rehabilitation , psychiatry , sleep quality , computer science , operating system
Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease(PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well asplace a huge burden on both patients and caregivers. The most cited sleep disorders in PD includedinsomnia, restless legs syndrome (RLS), rapid eye movement (REM), sleep behavior disorders(RBD), excessive daytime sleepiness (EDS) and sleep disordered breathing (SDB), which can appearalone or several at the same time. In this review, we listed the recommended pharmacologicaltreatments for common sleep disorders in PD, and discussed the recommended dosages, benefitsand side effects of relative drugs. We also discussed non-pharmacological treatments to improvesleep quality, including sleep hygiene education, exercise, deep brain stimulation, cognitive behaviortherapy and complementary therapies. We tried to find proper interventions for different types ofsleep disorders in PD, while minimizing relative side effects.