Open AccessVoxel-wise Functional Connectivity of the Default Mode Network in Epilepsies: A Systematic Review and Meta-Analysis
Author(s) -
Sisi Jiang,
Hechun Li,
Linli Liu,
Dezhong Yao,
Cheng Luo
Publication year - 2022
Publication title -
current neuropharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.955
H-Index - 73
eISSN - 1875-6190
pISSN - 1570-159X
DOI - 10.2174/1570159x19666210325130624
Subject(s) - default mode network , cuneus , neuroscience , epilepsy , task positive network , temporal lobe , posterior cingulate , middle frontal gyrus , idiopathic generalized epilepsy , superior frontal gyrus , middle temporal gyrus , medicine , psychology , functional connectivity , cognition , precuneus
Default Mode Network (DMN) is recognized to be involved in the generation and propagation of epileptic activities in various epilepsies. Converging evidence has suggested disturbed Functional Connectivity (FC) in epilepsies, which was inferred to be related to underlying pathological mechanisms. However, abnormal changes of FC in DMN revealed by different studies are controversial, which obscures the role of DMN in distinct epilepsies.