Open AccessThe Investigation into Neurotoxicity Mechanisms of Nonylphenol: A Narrative Review
Author(s) -
Mandana Lotfi,
Amir Hossein Hasanpour,
Ali Akbar Moghadamnia,
Sohrab Kazemi
Publication year - 2021
Publication title -
current neuropharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.955
H-Index - 73
eISSN - 1875-6190
pISSN - 1570-159X
DOI - 10.2174/1570159x18666201119160347
Subject(s) - neurotoxicity , toxicant , neuroscience , nonylphenol , oxidative stress , hippocampus , medicine , bioinformatics , biology , chemistry , endocrinology , toxicity , environmental chemistry
Nonylphenol (NP), a chemical compound widely used in industry, is the result of the nonylphenol ethoxylate decomposition and it is known as an estrogen-like compound. Numerous studies and researches have shown that it has many destructive functions of various organs such as the brain. This toxicant causes oxidative stress in the cortex and hippocampus cells, which are two essential regions to preserve memory and learning in the brain.