Neuroprotection: The Emerging Concept of Restorative Neural Stem Cell Biology for the Treatment of Neurodegenerative Diseases | Zendy

Fiorella Piemonte | Zendy; Ferdinando Rossi | Zendy; B Carletti | Zendy

Open Access

Neuroprotection: The Emerging Concept of Restorative Neural Stem Cell Biology for the Treatment of Neurodegenerative Diseases

Author(s) -

Fiorella Piemonte,

Ferdinando Rossi,

B Carletti

Publication year - 2011

Publication title -

current neuropharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.955

H-Index - 73

eISSN - 1875-6190

pISSN - 1570-159X

DOI - 10.2174/157015911795596603

Subject(s) - neuroprotection , neuroscience , neural stem cell , neurotrophic factors , stem cell , stem cell therapy , neurotrophin , medicine , biology , microbiology and biotechnology , receptor

During the past decades Neural Stem Cells have been considered as an alternative source of cells to replace lost neurons and NSC transplantation has been indicated as a promising treatment for neurodegenerative disorders. Nevertheless, the current understanding of NSC biology suggests that, far from being mere spare parts for cell replacement therapies, NSCs could play a key role in the pharmacology of neuroprotection and become protagonists of innovative treatments for neurodegenerative diseases. Here, we review this new emerging concept of NSC biology.

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