Open AccessIdentification of HnRNP Family as Prognostic Biomarkers in Five Major Types of Gastrointestinal Cancer
Author(s) -
Xianghan Chen,
Ruining Gong,
Jia Wang,
Boyi Ma,
Ke Lei,
He Ren,
Jigang Wang,
Chenyang Zhao,
Lili Wang,
Qing Yu
Publication year - 2022
Publication title -
current gene therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 71
eISSN - 1875-5631
pISSN - 1566-5232
DOI - 10.2174/1566523222666220613113647
Subject(s) - cancer , colorectal cancer , immunohistochemistry , gastrointestinal cancer , liver cancer , medicine , biology , oncology , pathology , bioinformatics , cancer research
Heterogeneous nuclear ribonucleoproteins (hnRNPs), a large family of RNAbinding proteins, have been implicated in tumor progression in multiple cancer types. However, the expression pattern and prognostic value of hnRNPs in five gastrointestinal (GI) cancers, including gastric, colorectal, esophageal, liver, and pancreatic cancer, remain to be investigated.