Open AccessEffect of the Phragmitis Rhizoma Aqueous Extract on the Pharmacokinetics of Docetaxel in Rats
Author(s) -
Sarah J. Shin,
No Soo Kim,
Young Ah Kim,
Hea Ry Oh,
OkSun Bang
Publication year - 2019
Publication title -
combinatorial chemistry and high throughput screening
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 64
eISSN - 1875-5402
pISSN - 1386-2073
DOI - 10.2174/1386207322666190419110724
Subject(s) - pharmacokinetics , pharmacology , docetaxel , cmax , medicine , bioavailability , vomiting , electron paramagnetic resonance , chemistry , anesthesia , chemotherapy , physics , nuclear magnetic resonance
Traditionally, Phragmitis rhizoma has been prescribed to relive a fever, vomiting, dysuria, and constipation, and to promote secretion of fluids. In addition, recent studies have reported its efficacy as a diuretic and antiemetic. Our previous study demonstrated that the Phragmitis rhizoma aqueous extract (EPR) ameliorates docetaxel (DTX)-induced myelotoxicity.