Open AccessDesign and Synthesis of Quinolizidine Derivatives as Influenza Virus and HIV-1 Inhibitors
Author(s) -
Zhao Dang,
Li Zhu,
Linghai Xie,
KuoHsiung Lee,
Faisal Malik,
Zhijun Li,
Li Huang,
Chin-Ho Chen
Publication year - 2021
Publication title -
current medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 174
eISSN - 1875-533X
pISSN - 0929-8673
DOI - 10.2174/0929867328666201229121802
Subject(s) - virus , quinolizidine , virology , viral replication , natural product , influenza a virus , potency , biology , chemistry , in vitro , stereochemistry , biochemistry , alkaloid
We have previously reported that a quinolizidine natural product, aloperine, and its analogs can inhibit influenza virus and/or HIV-1 at low μM concentrations.