Open AccessToxic effects of non-acute lead exposure on animal model
Author(s) -
Gheorghița Isvoranu,
Daniela Ionela Popescu,
Elena Codrici,
Simona Mihai,
AnaMaria Enciu,
Gina Manda,
Marco Perreto,
Cristiana Tănase
Publication year - 2019
Publication title -
proceedings book
Language(s) - English
Resource type - Journals
eISSN - 2457-8371
pISSN - 1843-5831
DOI - 10.21698/simi.2019.fp35
Subject(s) - lead acetate , toxicity , lead (geology) , lead poisoning , lead exposure , physiology , medicine , acute toxicity , toxicology , pharmacology , biology , paleontology , cats , psychiatry
Lead, a high-risk environmental pollutant and extensively used by industry, is one of the most widely outspread toxic metal today. Lead toxicity is a public health problem both for the children and for the adults. Lead does not have any useful functions in the body, instead it produces only harmful effects once it gets into the body. In this study, we investigated the toxicity of lead in an animal model of non-acute exposure. Experimental groups received treatment of aqueous solution lead acetate at different doses and time of administration. Toxic effects of lead were investigated on haematological and behaviour of treated rats. We noticed the disturbances of both haematological parameters and behaviour. Our results indicated that non-acute exposure to lead induced toxic effects in the blood, and central nervous system of adult Wistar rats.