Open AccessCharacteristics of gram-negative microflora isolated from the blood of cardiac patients over 5 years
Author(s) -
Л. М. Самойлова,
А. Н. Шилова,
Ю. Н. Горбатых,
Sergey Prokhorov,
О. В. Струнин,
М. А. Новикова
Publication year - 2015
Publication title -
patologiâ krovoobraŝeniâ i kardiohirurgiâ/patologiâ krovoobrašeniâ i kardiohirurgiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.136
H-Index - 3
eISSN - 2500-3119
pISSN - 1681-3472
DOI - 10.21688/1681-3472-2014-2-49-54
Subject(s) - antibiotics , amikacin , bacteremia , netilmicin , microbiology and biotechnology , piperacillin , gram negative bacteria , tazobactam , medicine , bacteria , piperacillin/tazobactam , gram positive bacteria , biology , imipenem , antibiotic resistance , pseudomonas aeruginosa , gentamicin , escherichia coli , tobramycin , biochemistry , genetics , gene
Currently gram-negative bacteria are recognized as the most problematic pathogens. The authors studied the incidence of bacteremia caused by gram-negative microflora and its sensitivity to antibiotics in patients who underwent cardiac surgery. We analyzed the results of blood tests over a period of 5 years, from 2007 to 2011. During this period, 216 strains of gram-negative bacteria were identified. Enterobacteria accounted for 57.4% (124) of the structure of the gram-negative flora, while 42.6% (92) were glucose non-fermentative gram-negative bacteria. The prevailing pathogens detected when studying cardiac patients' blood were K. pneumoniae (25.5%) and P. aeruginosa (15.3%). The infections caused by K.pneumoniae are most efficiently treated by using carbapenems. As for P. aeruginosa, the most efficient antibiotics to fight this pathogen are piperacillin/tazobactam, amikacin, netilmicin. Carbapenems should be prescribed only after the sensitivity of microorganisms to these antibiotics is determined.